The studies we read
Research on the ingredients we formulate with — not claims about our patches.
How to read this page
Every study below is independent, peer-reviewed research on an individual ingredient — in the format, dose, and duration the researchers used (oral supplementation unless noted). We share it as general education about the ingredients we formulate with. None of it is a study of Slap On patches, and none of it is a promise about what our products will do for you.
Research on delivery formats
What this research is (and isn't)
Scientists have studied how vitamins, amino acids, and plant compounds behave in different transdermal formats — microneedles, nanoemulsions, and lipid-based gels — in the laboratory. These are studies of formulation science, not of Slap On patches.
~72.9% of vitamin B12 released in 5 hours
A 2019 study of rapidly dissolving bilayer microneedle arrays reported that about 72.9% of their vitamin B12 load was released across skin over 5 hours in laboratory testing.
Microneedle study, 2019 · PubMed~3.37× higher GABA skin permeation vs a plain solution
A 2024 study in Cosmetics reported that a GABA nanoemulsion with a penetration enhancer permeated skin about 3.37 times more than a standard GABA solution in laboratory diffusion-cell testing.
Formulation study, 2024 · CosmeticsWithanolides formulated into a transdermal gel
A 2013 study formulated a standardized Withania somnifera (ashwagandha) leaf extract into a transdermal gel and evaluated its withanolide skin permeation in laboratory testing.
Formulation study, 2013 · J. Med. Sci.This is independent research on formulation science and delivery formats — none of it is a study of Slap On patches, and we make no claims about how our patches interact with your body. We read it because it informs how we think about ingredient stability, formulation quality, and patch design. Our patches are formulated with these ingredients.
Based on peer-reviewed human clinical studies of these individual ingredients in the formats, doses, and durations studied (oral supplementation unless noted). These studies describe ingredient research, not results from our products — Slap On patches have not been studied in clinical trials.
These statements have not been evaluated by any regulatory authority. This product is not intended to diagnose, treat, cure, or prevent any disease, and is not a substitute for professional medical advice.